Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a4c41c53e82cdf97e3f0eda90224c45 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16634 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-245 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
filingDate |
1991-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cdbb99a4c403643705fc5d8bc2e9cba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01147b2c5b6b428fad570cbf5dc868ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e981ba2357c771a06a93ad983f22dec2 |
publicationDate |
1999-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0953648-A2 |
titleOfInvention |
Viral defective vaccine produced by transcomplementing cell line |
abstract |
A mutant virus for use as a vaccine, wherein the genome ofnthe virus is defective in respect of a gene essential fornthe production of infectious virus. In one aspect thenmutant virus is capable of protecting a susceptible speciesnimmunized therewith against infection by the correspondingnwild-type virus. In another aspect, the mutant virus actsnas a vector for an immunogenic protein derived from anpathogen and which is encoded by foreign DNA incorporatednin the mutant virus. The mutant virus can be produced inna recombinant host cell which expresses a genencomplementing the defect. The mutant virus is preferablyninfectious for the host to be protected, but the defectivengene allows expression in the infected host of at leastnsome of the viral genes, which can provoke a cell-mediatednimmune response. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1683858-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1683858-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0136651-A1 |
priorityDate |
1990-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |