http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0953360-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
filingDate | 1998-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c44df911eb5ec440e596edf778698781 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a46c553980904ca8f1141f2362094f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef662cb6605fdeae77ef92a9ce588ae5 |
publicationDate | 1999-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0953360-A1 |
titleOfInvention | Technetium-99m radiolabelled diethylene triamine pentaacetic acid diester and process for the preparation of technetium-99m diethylene triamine penta-acetic acid diester |
abstract | The present invention relates a technetium-99m radiolabelledndiethylene triamine pentaacetic acid diester kit for the diagnosisnof renal disorders. n Accordingly, the present invention provides a technetium-99mnradiolabelled diethylene triamine pentaacetic acid diester kitnfor the diagnosis of renal disorders wherein technetium-99mndiethylene triamine pentaacetic acid dimethyl ester has Rfnvalue = zero in silica gel / acetone TLC system and Rf value = 1nin silica gel / acetonitrile water (1:1) TLC system and technecium-99mndiethylene triamine pentaacetic acid dimethyl esternmovement is of the order of half of the distance as compared tonthe standard compound (technecium-99m diethylene triamine pentaaceticnacid) on conducting paper electrophoresis. n The process for the preparation of a technetium-99m radiolabelledndiethylene triamine pentaacetic acid diester kit for thendiagnosis of renal disorders comprises:n (a) Adding appropriate amount of stannous ion to a dilute aqueousnsolution of diethylene triamine pentaacetic diester preparednby known methods (b) Keeping the resultant solution abtained in step (a) in annevacuated rubber sealed injection vial flushed with nitrogen; (c) lyophilising the said kit and storing the lyophilised productnan obtained in step (b) at 4°C; (d) radiolabelling the said lyophilised product with Tc-99m bynallowing the kit to attain the room temparature before additionnof 99m TcO 4 ; (e) shaking the kit vigorously to obtain the radiolabellednproduct available for use within a period of an hour. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016501867-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2922816-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9546129-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9969681-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8961924-B2 |
priorityDate | 1998-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.