| abstract |
Compounds of formula (I) or pharmaceutically, veterinarily or agriculturally acceptable salts thereof, or pharmaceutically, veterinarily or agriculturally acceptable solvates of either entity, wherein R1 is 2,4,6-trisubstituted phenyl or 3,5-disubstituted pyridin-2-yl; R3 is C1-C4 alkyl optionally substituted with hydroxy or with one or more halo; cyano, C1 to C5 alkanoyl or phenyl; R5 is hydrogen, C¿1? to C4 alkyl, amino or halo; R?2 and R4¿ are each independently selected from hydrogen, C¿1? to C4 alkyl, fluoro, chloro and bromo or, together with the carbon atom to which they are attached, form a C3 to C6 cycloalkyl group; R?6 and R8¿ are each independently selected from hydrogen, C¿1? to C4 alkyl, fluoro, chloro and bromo; or, when R?2 and R4¿ do not form part of a cycloalkyl group, R?2 and R6¿, together with the carbon atoms to which they are attached, may form a C¿5? to C7 cycloalkyl group; and R?7¿ is hydrogen, C¿1? to C4 alkyl optionally substituted with one or more halo, or C1 to C4 alkoxy; are parasiticidal agents. |