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filingDate 1997-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1096ee13e258b4c8cd8a86ac6aaf2f7c
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publicationDate 1999-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0944726-A1
titleOfInvention Methods for modulating metabolic pathways of micro-organisms and micro-organisms obtainable by said methods
abstract The invention provides methods for changing the metabolic pathways of micro-organisms in the presence of a certain carbon source and uses of such changes, as well as micro-organisms and uses of such changes, as well as micro-organisms produced by these methods. In a preferred embodiment the invention provides new yeast strains with improved biomass yields, a process to obtain these yeasts and the potential application of these yeasts are provided. The biomass yield is improved by the introduction into a yeast of a DNA construct conferring altered expression of a gene encoding a protein controlling transcription of a number of glucose-repressed genes. The yeasts are less sensitive to glucose repression, resulting in an increase in respiratory capacity, reduction of ethanol production and increased conversion of sugar into biomass.
priorityDate 1996-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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