| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b0f9f3fe447fa1aecbab74fc1d4f5d2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-976
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96433
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-045 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6424
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate |
1997-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31ed1caa298e387552b5dee4be96b71b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7defbcb3200dd46231628560fc68a63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e6dccaa049051ff156cb9d164b05923
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c32ded57aebcf5f12c2856dddd1a0987
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f970cad01a9ebf628212b657deae2a96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52e523632201374f2dacc23291d04901 |
| publicationDate |
2005-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0943008-B1 |
| titleOfInvention |
Metal mediated serine protease inhibitors |
| abstract |
The present invention relates to serine protease inhibitors having a P site binding moiety and a divalent cation(s) chelating moiety which are pre-prepared as divalent cation(s) complexes or combined with the serine protease in the presence of divalent cation(s) and methods for identifying and using the inhibitors. The compounds are shown to have high inhibitory activity when complexed to divalent cation(s) and are useful in various processes associated with serine protease isolation and inhibition. |
| priorityDate |
1996-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |