Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a135a933620c99beab01d4ac785d25 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1278 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate |
1997-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2002-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d763e16692df38a9910c6f5ced39445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcd51afc7ee064b5406d854b125a49ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a4741781c916cb6681c795c3be49555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aff441919568bb72cda1a8d3198f58ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb9650ea0d58fc2a15f7e3f0255330e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_094b01a0249b96abe10850914dc15207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84145081391ebb8efd6fbf9942ec29f3 |
publicationDate |
2002-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0941065-B1 |
titleOfInvention |
Ionophore-mediated liposome loading of weakly basic drug |
abstract |
Novel methods are provided for loading a weakly basic drug into liposomes utilizing an electoneutral transport system. In these methods, ionophores are utilized with liposomes having a metal ion gradient to facilitate the exchange of metal ions for protons. The transported metal ion will, in some embodiments, be complexed with a chelating agent which is present in the external media. |
priorityDate |
1996-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |