abstract |
A heterocyclic amide compound of the formula (I)n nwherein each symbol is as delined in the specification, a pharmacologicallynacceptable salt thereof, a pharmaceutical composition thereof and anpharmaceutical use thereof. The heterocyclic amide compound and anpharmacologically acceptable salt thereof of the present invention have superiorninhibitory action on chymase group in mammals inclusive of human, and can benadministered orally or parenterally. Therefore, they are useful as chymaseninhibitors and can be used for the prophylaxis and treatment of various diseasesncaused by chymase, such as those caused by angiotensin II. |