Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8ab7f32a9777e6419ea800f0923ee0e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
1997-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6ba1450f3bd408be7f6c2dcba101af3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56794f1a3fb073a2565fd3ddbba39b1b |
publicationDate |
1999-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0935649-A1 |
titleOfInvention |
Artificial rheumatic pannus tissues and diagnostic method for detecting rheumatoid arthritis |
abstract |
The invention concerns rheumatic pannus tissue which forms pannus-type villi and preferably contains class II HLA positive macrophage-type cells and vimentin-producing fibroblast-type cells. The invention also concerns a process for preparing rheumatic pannus tissue, and the use of rheumatic pannus tissue for discovering pharmacologically effective substances. The invention further concerns a method and diagnostic procedure for the in vitro diagnosis of rheumatoid arthritis, which method is characterized in that the absence of or reduction in the number of CD21 on B-cells in the synovial fluid is detected. |
priorityDate |
1996-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |