http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0934324-A4

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-572
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572
filingDate 1997-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b87a0ae8da37683bb42ec77af2f3ee36
publicationDate 2000-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0934324-A4
titleOfInvention PROCESS FOR SYNTHETIZING INTERMEDIATE PRODUCTS OF THE CARBAPENEM SIDE CHAIN
abstract A process for the synthesis of an N-(di-substituted phosphoryl)-trans-4-hydroxy-L-proline of formula (I) is disclosed, wherein R<1> and R<2> independently represent C1-18 alkyl, phenyl or phenyl-substituted C1-18 alkyl, or R<1> and R<2> are taken in combination to represent C2-4 alkylidene or phenyl. Trans-4-hydroxy-L-proline is reacted with a di-(substituted) phosphite of formula (III) in the presence of sodium hypochlorite and sodium hydroxide to produce a compound of formula (I).
priorityDate 1996-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 24.