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filingDate 1997-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98ab677446c41796718e59aaf81fe8bc
publicationDate 1999-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0934261-A1
titleOfInvention Process for producing mercaptoalkanesulfonates and phosphonates and derivatives thereof
abstract A process for synthesizing disulfides and sulfhydryl compounds which are useful pharmaceuticals. The process includes a two step, single pot process for preparing disulfides from an alkenyl sulfonate salt. The disulfides are useful as toxicity mitigating agents of chemotherapeutic drugs, such as certain platinum complexes, and as use therapeutic drugs for a variety of conditions in mammals. The two step process involves first the conversion of the starting reagent to a mercaptane sulfonate, then an oxidation to the desired disulfide.
priorityDate 1996-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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