abstract |
This invention provides terpenoid lactone compounds, and processes fornproducing the terpenoid lactone compounds, which comprise cultivating Oidiodedronngriseum FERM BP-5778 and then isolating the terpenoid lactone compounds fromnthe fermentation broth. The present invention also provides a pharmaceuticalncomposition comprising the terpenoid lactone compound, which is useful in thentreatment of IL-1 and TNF mediated diseases or the like. |