http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0931564-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa48a431ce250933eb0fdd7a1caf3f30 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-044 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 |
| filingDate | 1989-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1755da606ce0ad5c9398419cf18e709b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4dbc3ecce5f13fc3332285b11c53d22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2b7e31f7fbaa721f35ed8276eab1e06 |
| publicationDate | 2003-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0931564-B1 |
| titleOfInvention | Electrotransport drug delivery |
| abstract | Membrane for controlling agent delivery from an iontophoretic agent delivery device adapted to deliver the agent through an intact body surface is claimed,the device having a reservoir contg. the agent to be delivered and being connectable to a source of electrical power for driving the agent from the reservoir and through the body surface, in which the membrane is interposed between the agent reservoir and the body surface, the membrane permitting electrically-assisted flux (JEK) of the agent and preventing passive flux (Jp) of the agent, the membrane exhibiting a (JEK + Jp)/Jp ratio of at least 4, a voltage drop across the membrane of less than 1 volt and a Jp of less than 100 microgram/hr-cm2. The membrane may be formed by dissolving in a solvent, eg CH2Cl2 and CH3OH, 60-95 pts. wt. of cellulose acetate and 5-40 pts. wt. of a water soluble material, eg. polythylene glycol, having a mol. wt. at least great as the agent mol. wt., casting the membrane, evapg. the solvent and leaching out all of the water soluble material. Alternatively the membrane may comprise a mixt. of a hydrophilic resin, eg. PVP or an ion exchange resin having a functional gp. selected from sulphonic acid, carboxylic acid, imidodiatcetic acid and quaternary amines and hydrophobic polymer, eg. an ethylene vinyl acetate polymer having a vinyl acetate content of 1-40 wt. Also claimed is a method for testing performance characteristics of an iontophoretic agent delivery device adapted for delivering an agent through an intact body surface, using the membrane. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8862223-B2 |
| priorityDate | 1988-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 242.