abstract |
Compounds of formula In nas well as pharmaceutically usable salts and esters thereof, wherein R 1 , R 2 and R 3 haventhe significance given in claim 1, inhibit the binding of adhesive proteins to thensurface of different types of cell and accordingly influence cell-cell and cell-matrixninteractions. They can be used in the form of pharmaceutical preparations for thencontrol or prevention of neoplasms, tumour metastasing, tumour growth,nosteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosisnfollowing vascular intervention, psoriasis, arthritis, fibrosis, kidney failure as well asninfection caused by viruses, bacteria or fungi. |