Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ce023a6c13740cb05a67332f11a29f9 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-333 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-487 |
filingDate |
1997-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e07b86bd517bb5e379ca23d18c1ffdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abfbc42fdba5b2058b72c953371c29ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9756d7428313ee8c52f6ab35b3c0b84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f311df1fe137555421e3fc36ddf854b |
publicationDate |
1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0925267-A1 |
titleOfInvention |
Racemization process for optically active carboxylic acids or salts or esters thereof |
abstract |
Optically active carboxylic acids, salts or esters, such as the profen-type compounds, are racemized in the presence by nitrogenous bases such as methylbenzyl-amine by heating an aqueous solution of such optically active compounds at a temperature of from 80 °C to 200 °C in the presence of a catalytically effective amount of an alkali metal hydroxide. The process not only enables conversion of inactive or undesirable enantiomers of compounds such as Naproxen or Ibuprofen into a usable, desirable enatiomers in an efficient and economical manner, but avoids conversion of the nitrogenous base into amide. Thus the deleterious consequences of amide formation are avoided. |
priorityDate |
1996-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |