abstract |
A process is provided for producing a 2-amino-1phenylethanol derivative comprising;allowing (a) a compound shown by the general Formula (III)or (b) a compound shown by the general Formula (IV)wherein R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup> and R<sup>5</sup> represent a hydrogen atom etc; Z represents a hydrogen atom or a protective group for hydroxyl group and X represents a halogen atom,to react with a compound of the Formula Y-NH<sub>2</sub> wherein Y represents a hydrogen atom or a group which can be left in the reaction, further, when Y is the group which can be left in the reaction, allowing Y to be left,to obtain a compound shown by the general Formula (VI)which comprises adding an acid to the reaction products containing the compound of the general Formula (VI) to precipitate or crystallize said compound as a salt and, thereby, isolating the compound of the general Formula (VI). |