| abstract |
The invention relates to a nucleic acid molecule,ncalled 〈〈 ribozyme 〉〉, having endoribonuclease activity,ncomprising at least one hybridising region and at leastnone catalytic region, said hybridising region beingncomplementary to one or more target regions of thengenomic (+) RNA of a potyvirus, and/or to one or morentarget regions of the replicative (-) strand RNA of anpotyvirus, with the proviso that the said target regionndoes not consist of the GUC triplet located at positionn8122-8124 of the PVYn strain or the equivalent tripletnof other potyviruses. |