| abstract |
The invention relates to new peptidyl-arginine aldehyde compounds of formula (I)whereinQ represents an acyl group of formula Q'-OCO, wherein Q' represents an alkyl-group with 1-3 carbon atoms,D-Xaa represents a 3-cyclobutyl-D-alanyl- or 3-cyclopentyl-D-alanyl group,Pro represents an L-prolyl group, andArg represents an L-arginyl group,and acid-addition salts thereof, and pharmaceutical compositions comprising them, which are suitable for the prevention and cure of thrombosis and accelerated blood clotting. |