Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be944a7839fc8cabe752928d03dafaa4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10362 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10322 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4712 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-57 |
filingDate |
1994-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2002-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10af4557e35322bb6a28e5958e7b2329 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea77f866c0bea07555c05b384339477e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_373712013069b1c53de01fc4ee081378 |
publicationDate |
2002-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0919625-B1 |
titleOfInvention |
Defective Adenoviruses |
abstract |
New replication-defective adenoviruses are selected from: (a) those that are derived from a natural adenovirus and lack at least the coding sequences of the E1B region and/or at least part of the E4 region; (b) those that are derived from a natural adenovirus other than a human type 5 adenovirus (Ad5) and lack part of the encapsidation region; (c) those that are derived from Ad5 and lack the part of the encapsidation region corresp. to nucleotides 270-346 in the Genbank M73260 sequence; and (d) those that are derived from Ad5 and lack the part of the encapsidation region corresp. to nucleotides 184-273 in the Genbank M73260 sequence. Also claimed is a eukaryotic cell contg. an adenovirus as above. Also claimed are: (1) a complementation line comprising a cell line contg. a complementation element which comprises at least part of the E1 region of a natural adenovirus and lacks the 5' ITR sequence, the element being integrated into the genome or inserted into a vector: and (2) a process for producing a defective adenovirus as above, comprising introducing the virus into a complementation line as above, culturing the cell line, and recovering the virus from the culture supernatant. |
priorityDate |
1993-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |