| abstract |
The present invention provides a peptide compound of formula Z1-K-A-Q-X1-K-K-N-K-H-R-H-S-X2-T-Z2 [SEQ ID No. 1] where: X1 represents S or Y, X2 represents T or I, Z1 represents the N terminus of the peptide, or from 1 to 47 amino acids, Z2 represents the C terminus of the peptide, a terminal amide group, or from 1 to 77 amino acids; or a variant of this peptide which contains one or more internal deletions, insertions or substitutions and which substantially retains anti-coagulant properties of apoB-100. |