| abstract |
A process for the production of trans- (R, R) -actinol by diastereoselective transfer hydrogenation ofnLevodione consists of (R) -evodione in the presence of a hydrogen donor, which is also used asnSolvent and an amino-amide-ruthenium complex,nin particularnof the formula RuH (L {-H}) (Y), in which Y is a neutral ligand and L is an optical one, if appropriatenactive monosulfonylated diamine ligands as defined in the description,nmean to hydrogenate.n n n The invention also relates to a certain part of the amino-amide-ruthenium complexesnas well as thencorresponding precursors to these complexes, which have halogen instead of H. ThenProduct of the process according to the invention, trans- (R, R) -actinol, is known as an important building blocknfor the synthesis of carotenoids, e.g. Zeaxanthin. The process turns trans- (R, R) -actinolninndelivered particularly high enantiomeric and diastereomeric purity. |