http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0913397-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-27 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-27 |
| filingDate | 1997-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1efe9d02a1d442054a094a8c4befc79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87d2b57f22db9b177d1d6404bfcbff77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70ba4066f2276b64b5c8d92f75eebd9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa69a99483a2954a30dc17ba3f327f4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c82cd738179a0f9b028432450a9d2a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4c2f4dfb54616932868c8c975070473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58e396b76d43e8e7855278c7d3b99525 |
| publicationDate | 1999-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0913397-A1 |
| titleOfInvention | A proces for the synthesis of 1-(4-Arylpiperazine-1-y1)-3-(2-oxypyrrolidin/piperidin-1-y1) propanes as therapeutic agents for hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders |
| abstract | A process of preparing novel compounds of formula 1n nWherein Ar represents a phenyl ring substituted by the groups like halo,nalkoxy, alkyl or heteroaryl, n=1 or n=2; said compounds are used asnpotential therapeutic agents for hypertension, ischemic, cardiovascularnand other adrenergic receptors related disorders, said process comprisingncondensing 2-pyrrolidone of formula 2 (n=1) or 2-piperidone of formula 2n(n=2) with 1-[4-substituted arylpiperazin-1-yl]-3-chloropropanes ofnformula 5 where Ar represents a phenyl ring substituted by the groups likenhalo, alkoxy, alkyl or heteroaryl in the presence of a base and organicnsolvent at a temperature ranging from 120-150°C for a period varyingnbetween 90 min. to 14 hrs. to produce the corresponding 1-[4-substitutednarylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes of formulan1. |
| priorityDate | 1997-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 291.