| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e26de8d88c7b32804d869e560ae6ac52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2d8a269e3211031c41b7d4becfc1b3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-334
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-335 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1136 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-173 |
| filingDate |
1997-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b26f3559471493981151e60dfa2e00e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d5180e15a0203659747f6fa5a5d094a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3620cded294f3e6ed4d31b6d5d503942
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9f0f6e5ee8ffcf86f54db3c237f8980
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cf1fe3f85717cfbb346ecca0d28f126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbc2b9d45914b1b052646c4ce0fb3585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_deec2184320d1dd819313e63e3c6a2bf |
| publicationDate |
1999-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0910634-A2 |
| titleOfInvention |
ANTISENSE INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEgF/VPF) EXPRESSION |
| abstract |
The present invention relates to the inhibition of vascular endothelial growth factor expression with oligonucleotides. The oligonucleotides of the present invention are thought to bind to target nRNA in a sequence specific manner and prevent expression of the encoded gene. Chemical modifications of the oligonucleotides for increasing their stability and binding efficiency are disclosed. These modifications increase the stability and the efficiency of the oligonucleotides contemplated in this invention. Oligonucleotides compositions can be used in ex vivo therapies for the treatment of macrophages or in vivo therapies by injection, inhalation, topical treatment or other routes of administration. |
| priorityDate |
1996-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |