http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0910575-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-23 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-23 |
filingDate | 1997-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2002-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_007dcea3bf251ecdc20a64537c2329f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80f9f4029189a262b71f917c708fd76e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd66464fcb63412b951e696147598acc |
publicationDate | 2002-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0910575-B1 |
titleOfInvention | Method for producing peptides |
abstract | A peptide of the formula:wherein R1 represents His, Tyr, Trp or p-NH2-Phe, R2 represents Tyr or Phe, R3 represents an optionally substituted Gly or an optionally substituted alpha-D-amino acid residue, R4 represents Leu, Ile or Nle, R6 represents (1) Gly-NH-R7, wherein R7 represents a hydrogen atom or an alkyl group which may optionally be substituted with a hydroxyl group, or (2) NH-R8, wherein R8 represents a hydrogen atom, an alkyl group which may optionally be substituted with a hydroxyl group or an ureido group (-NH-CO-NH2), is produced advantageously in an industrial scale by reacting a peptide of the formula:wherein R1, R2 and R3 have the same meanings as defined above or its salts, with a peptide of the formula:wherein R4 and R6 have the same meaning as defined above and R5 represents Arg which has been protected or its salts, to produce a peptide of the formula:wherein R1, R2, R3, R4, R5 and R6 have the same meanings as defined above or its salt, and then subjecting thus obtained peptide (I') to a de-protecting group reaction. |
priorityDate | 1996-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 151.