http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0910416-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56666880a5e2b7703e98a4f9b2d9daf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e93d357c3fcb571238ff08afe6072cd |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-072 |
filingDate | 1997-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc82991623131748f0937b9cf8bc5e36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3e0228a61e4c2326890a2b57cec6dfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc6de1d83e354c7bba4edfefbeb86718 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e658872c880cc34b4a6e7cb2c972b4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7af6cb9a52aa3f4ac40d4bc93cfa10c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9fe724a5a71133dcea76512fa546003 |
publicationDate | 1999-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0910416-A2 |
titleOfInvention | Radiopharmaceutical compositions capable of localizing at sites of thrombus |
abstract | A radiopharmaceutical capable of localizing at a site of thrombus containing activated platelets within a mammalian body is provided wherein the radiopharmaceutical comprises a linear peptidomimetic containing ligand capable of specifically binding to the GPIIb/IIIa integrin receptor of platelets in the thrombus and a radionuclide covalently bound to the peptidomimetic containing ligand. The ligand compositions of the invention are provided complexed with a selected metal radionuclide to form a diagnostic or therapeutic radiopharmaceutical to image a site of thrombus or provide radiotherapy to the site of thrombus, respectively. Methods of imaging a site of thrombus in a mammalian body by administering a diagnostically effective amount of the radiopharmaceutical composition of this invention complexed with a selected diagnostic metal radionuclide and methods of providing therapy to a site of thrombus in a mammalian body by administering a therapeutically effective amount of the radiopharmaceutical composition of this invention complexed with a selected therapeutic metal radionuclide are also provided as well as kits for preparing such radiopharmaceutical compositions. |
priorityDate | 1996-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 202.