| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381805eba6d034fc77bd230dd02e6e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_709b4a26ef028713f9b302509eb824d7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate |
1997-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8844c43491223c0fb4acd31d674c240
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53354af89e76632031a32fcf6409f488
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc84136a1c438791c05a86df139be268
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5662c3902a9226b2681d606c640530a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d93a88ffe0dc11612192f855e125e94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a18c8126f56bfbb50a761fad94285ea2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c87f62b8e6791c443a22b56bd5d34ad7 |
| publicationDate |
2002-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0907356-B1 |
| titleOfInvention |
Aerodynamically light particles for pulmonary drug delivery |
| abstract |
Improved aerodynamically light particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the aerodynamically light particles are made of biodegradable material and have a tap density of less than 0.4 g/cm<SUP>3 </SUP>and a mass mean diameter between 5 mum and 30 mum. The particles may be formed of biodegradable materials such as biodegradable polymers. For example, the particles may be formed of a functionalized polyester graft copolymer consisting of a linear alpha-hydroxy-acid polyester backbone having at least one amino acid group incorporated therein and at least one poly(amino acid) side chain extending from an amino acid group in the polyester backbone. In one embodiment, aerodynamically light particles having a large mean diameter, for example greater than 5 mum, can be used for enhanced delivery of a therapeutic agent to the alveolar region of the lung. The aerodynamically light particles incorporating a therapeutic agent may be effectively aerosolized for administration to the respiratory tract to permit systemic or local delivery of wide variety of therapeutic agents. |
| priorityDate |
1996-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |