http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0900775-A4

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filingDate 1996-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6369f9f0175d0a5d789532dedd0f783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eaa4902483289468ed8b056fe955aa1
publicationDate 1999-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0900775-A4
titleOfInvention PROCESS FOR PRODUCING CATECHOL DERIVATIVES
abstract An improved process for producing catechol derivatives (1) useful as intermediates for compounds useful as drugs or agricultural chemicals, which comprises the reaction steps shown above. In said process (I), R represents alkyl, cycloalkyl, aralkyl, alkoxy, halogeno, allyl or aryl, and R1 represents a hydroxy-protecting group. The process is characterized in that formylation as the first step is conducted in the presence of a tin catalyst in two stages, first at 60 to 85 °C to a conversion of 30 to 80 % and then at 95 to 105 °C to completion, to thereby obtain a salicylaldehyde (3) in a high yield with a high selectivity. The objective catechol derivatives (1) having a high purity are hence obtained in a high yield.
priorityDate 1995-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 28.