http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0895784-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate | 1997-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1a3592fbc3e5722f4f4018986c457cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfd53505865f822a6ee6c06233911b3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5715dfecf8dc9254d0a85512ef0f4be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65f4c2fe9b0a527150841a444a59b67c |
publicationDate | 1999-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0895784-A1 |
titleOfInvention | Medicament composite |
abstract | Disclosed is a drug complex of a drug having anhydroxyl group, which is capable of controlling the ratenof the release of the drug therefrom in blood, the drugncomplex being represented by the following formula (1):n nwherein A represents at least one carrier selected fromnthe group consisting of saccharides each having a carboxylngroup, polyethylene glycols each having a carboxylngroup, aliphatic carboxylic acids each having a carboxylngroup, and derivatives thereof each having a carboxylngroup; B represents at least one spacer comprised of ancompound having a amino group and a carboxyl group; Cnrepresents at least one drug having a hydroxyl group,nwherein the carrier A is bonded to the spacer B throughnan amide bond formed between the carboxyl group of thencarrier A and the amino group of the spacer B; and thenspacer B is bonded to the drug C through an ester bondnformed between the carboxyl group of the spacer B andnthe hydroxyl group of the drug C. The drug complex ofnthe present invention is capable of not only surelyncontrolling the rate of release of the drug therefrom,nbut also enhancing the transferability of the drug tontarget tissues and the pharmacological effect of thendrug. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6541508-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7119074-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6713454-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2002328093-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0119407-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0119407-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6380405-B1 |
priorityDate | 1996-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 219.