Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93e8f3f0e161df3d09d4b9a837a21e23 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-92 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-08 |
filingDate |
1998-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecb8d531f3deb40efdfe5a3271d93bef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1c0eec661d3f92ad352996634cbf006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57a2c8ba5071be453fc7d16d5847c75c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f17c336274521ece118753cbf51d4598 |
publicationDate |
2006-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0892054-B1 |
titleOfInvention |
Clostridium perfringens vaccine |
abstract |
The present invention relates to detoxified immunogenic derivatives of Clostridium perfringens beta -toxin or an immunogenic fragment thereof that have as a characteristic that they carry a mutation in the beta -toxin amino acid sequence, not found in the wild-type beta -toxin amino acid sequence. The invention also relates to genes encoding such beta -toxins, as well as to expression systems expressing such beta -toxins. Moreover, the invention relates to bacterial expression systems expressing a native beta -toxin. Finally, the invention relates to vaccines based upon detoxified immunogenic derivatives of Clostridium perfringens beta -toxin, and methods for the preparation of such vaccines. |
priorityDate |
1997-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |