| abstract |
A claimed composition comprises a peptide of formula (I), given in one letter amino acid code, and an appetite-suppressing or satiety-inducing agent, preferably administered with glucagon-like peptide (GLP)-1. X1HX2DGSFSDEMNTX3LDX4LAX5X6DFINWLX7X8TKITDX9 (I) X1 = absent, DFPEEVAIVEELGRR, DFPEEVTIVEELGRR, or a fragment of these; X2 = A or G; X3 = I or V; X4 = N, S or H; X5 = A or T; X6 = R or K; X7 = I or L; X8 = Q or H; X9 = absent, K, R, RK, KR, RR or KK. Also claimed is the use of a composition comprising a peptide of formula (I) for: (a) appetite suppression or satiety induction; and (b) prophylaxis and treatment of obesity or type II diabetes. |