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filingDate 1997-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_374c6d2c357e47e49b27dd51edcbdd36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_857dbb9197017f630409126d172c6ab2
publicationDate 1999-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0889874-A1
titleOfInvention 7-amino-2-heptenoates and their use in the preparation of methylphenidate
abstract PCT No. PCT/GB97/00811 Sec. 371 Date Sep. 25, 1998 Sec. 102(e) Date Sep. 25, 1998 PCT Filed Mar. 21, 1997 PCT Pub. No. WO97/35836 PCT Pub. Date Oct. 2, 1997The subject invention pertains to compounds of the formula Y1Y2N-(CH2)4-CH=C(Ph)-X wherein Y1 and Y2 are independently H or a removable blocking group, or Y1 and Y2 together are a removable divalent blocking group; and X is COOCH3 or a group convertible thereto. Such a compound may be cyclised, by Michael addition, to give methylphenidate, if necessary after removing blocking group(s) and converting X to COOCH3. The subject invention also pertains to methods for preparing compounds of the invention.
priorityDate 1996-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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