http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0883400-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ff905fdc49089f5f25746eaeb40190 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-006 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4453 |
| filingDate | 1997-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f40eeb11b899198d94efe03f26ab39f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8a21f56d6aa55df288035a21867c1b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ed6997a558b41150ee0e1b57f156838 |
| publicationDate | 1998-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0883400-A1 |
| titleOfInvention | Delivery system for localized administration of medicaments to the upper respiratory tract |
| abstract | The present invention pertains to delivery systems for the localized administration of a medicament to the upper respiratory tract. The delivery system comprises: (a) a save and effective amount of a medicament useful for treating the upper respiratory tract; (b) an ionic polysaccharide; and (c) a cross-linking agent. The present invention provides for the controlled, in situ formation of a thin, bioadhesive film which may bind to the buccal epithelial cells which form the surface of said upper respiratory tract. Said film formation occurs when the delivery system of the present invention comprising a medicament, an ionic polysaccharide and a cross-linking agent, in a pharmaceutically acceptable carrier, is slowly ingested by dissolution through salivation of the pharmaceutically acceptable carrier. By a series of cross-linking reactions, the cross-linking agent polymerizes the ionic polysaccharide to a film in the form of aggregates, which bind to the buccal epithelial cells in the upper respiratory tract. During the in situ cross-linking reaction, the medicament becomes entrapped in the bioadhesive polymer aggregate and thereafter is gradually released, i.e., becomes available through dissolution. |
| priorityDate | 1996-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 334.