| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21cd0c1d3449aaed46cbb766df7024ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_168dde4c7957f638c05b8d22f14f8189 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-814
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-816
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-815 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D67-00931
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-548
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D69-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D67-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3255
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3274
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3212
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3219
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3246
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3251
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3248 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-544
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D69-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-281
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-548
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-12 |
| filingDate |
1996-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_864714cb5f3b1a0c26e626a4832185e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47eab6fb0c56e001fffcbc0b638a4dd3 |
| publicationDate |
1998-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0880544-A1 |
| titleOfInvention |
Surface modified affinity separation membrane |
| abstract |
An affinity ligand (6) such as an antibody or enzyme, or a cell receptor complement is covently bonded to one end of a leash (4) formed of a difunctional spacer and/or bifunctional linking agent that has another end covalently bonded to interior pore surfaces (3) of a high flux semipermeable hydrogel membrane (1) to produce an affinity support for separation of biological molecules such as proteins, cells or cell fragments from solution. Pores of the membrane have an exclusion limit (molecular weight cut-off) selected to substantially restrict immobilized protein or other ligand to the surface of the membrane for maximization of available ligand binding capacity. The exclusion limit is also selected to permit the leash used for bonding of a ligand to the membrane to penetrate into pores and bond to interior pore surfaces of the membrane. |
| priorityDate |
1995-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |