abstract |
Compounds of the formula <IMAGE> I wherein R1 and R2 each individually are lower-alkyl or amino, A is <IMAGE> <IMAGE> <IMAGE> <IMAGE> B is hydrogen in A4, A5 and A6; <IMAGE> in A1-A6; lower-alkoxy in A4-A6; and lower-alkyl, styryl, phenylethynyl or benzoyloxy-lower-alkyl in A1 and A2; n is 0, 1 or 2; m, p are, independently 0, 1 and R3, R4, R5 and R6 each independently are hydrogen, halogen, lower-alkyl, trifluoromethyl, lower-alkoxy or nitro, and pharmaceutically acceptable acid addition salts thereof. These compounds are useful in the control or prevention of illnesses which are caused by disorders of the dopamine system, in particular psychotic illnesses such as schizophrenia. |