| abstract |
An intimal thickening inhibitory agent comprising,nas an active ingredient, a compound represented by formulan(1):n nwhereinn X represents an oxygen atom or a group of formulan(2):n nwherein n represents an integer of from 0 to 2, R 1 represents a hydrogen atom or an acyl group; R 2 representsna hydrogen atom, a lower alkyl group or a lower alkenylngroup; R 3 represents a lower alkyl group; and R 4 , R 5 , and R 6 ,nwhich may be the same or different, each represent a hydrogennatom or a substituted or unsubstituted alkyl group; or R 3 andnR 4 may be taken together to form a 5-membered ring; or R 5 andnR 6 may be taken together to form a cycloalkyl group; providednthat R 6 is nil when R 3 and R 4 are taken together to formnbenzofuran or benzo[b]thiophene. |