http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0863144-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b9036c33bbe3f4ea428655b76200f7c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
filingDate | 1997-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4185a01fe7ef1a5cba869d7bf9784628 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da3a2e497c7e59ca0c9bdb767b288e5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d42d63f0496179ccf15d8d59eec03b8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c355c4ace88f6649ad54663e3d1e04fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a86e62dbe9288c610b701e0ddfa67e6 |
publicationDate | 1998-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0863144-A1 |
titleOfInvention | Imidazoquinazoline derivatives |
abstract | The present invention provides imidazoquinazolinenderivatives represented by formula (I):n nwherein R 1 represents hydrogen, substituted ornunsubstituted lower alkyl, substituted or unsubstitutedncycloalkyl, substituted or unsubstituted bicycloalkyl,nsubstituted or unsubstituted tricycloalkyl or the like, R 2 nrepresents hydrogen, substituted or unsubstituted lower alkyl,nsubstituted or unsubstituted cycloalkyl, substituted ornunsubstituted bicycloalkyl, substituted or unsubstitutedntricycloalkyl, substituted or unsubstituted lower alkenyl,nsubstituted or unsubstituted aralkyl or the like, R 3 representsnhydrogen, substituted lower alkyl, substituted ornunsubstituted cycloalkyl, substituted or unsubstitutednbicycloalkyl, substituted or unsubstituted tricycloalkyl,nsubstituted or unsubstituted lower alkenyl, substituted ornunsubstituted aralkyl or the like, and R 2 and R 3 are combinednto represent a substituted or unsubstituted N-containingnheterocyclic group, X represents O or S, or pharmaceutically nacceptable salts thereof, which have potent and selectivencyclic guanosine 3',5'-monophosphate (cGMP)-specificnphosphodiesterase (PDE) inhibitory activity and arenuseful for treating or ameliorating cardiovascular diseasesnsuch as thrombosis, angina pectoris, hypertension, heartnfailure, arterial sclerosis, as well as asthma, impotence andnthe like. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03051346-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03051346-A2 |
priorityDate | 1996-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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