http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0862645-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-14 |
| filingDate | 1996-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5940780acebcc21befd6bffc8bad6ffc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d83fbdcb0e2e11d347da5524352318f |
| publicationDate | 2003-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0862645-B1 |
| titleOfInvention | Stereoselective microbial reduction process |
| abstract | A stereoselective reduction of compound of formula II to compound of formula I, which comprises adding compound of formula II to a culture broth of the Zygosaccharomyces bailii ATCC 38924, incubating the resulting mixture, and isolating a hydroxy compound of formula I, is described. A stereoselective reduction of a compound of formula IV to compound of formula III, which comprises adding a compound of formula IV to a culture broth of Schizosaccharomyces octosporus ATCC 2479, incubating the resulting mixture, and isolating a hydroxy compound of formula III is also described. The resulting compounds of formula I and III are useful as intermediates in the preparation of 1-(4-fluorophenyl)-3(R) -[3(S)-hydroxy-3-(4-fluorophenyl)propyl)]-4(S)-(4-hydroxyphenyl)-2-azetidionone which is a serum cholesterol lowering agent. |
| priorityDate | 1995-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.