abstract |
Method for removing viruses, in particular small non-envelopednviruses, from a plasma derived product, such as ProthrombinnComplex Concentrate. The method comprises prefiltration tonremove contaminating high molecular weight proteins, followednby nanofiltration through a membrane with an average pore sizenof 15 nm. The method is capable of removing > 5.1 log Caninenparvovirus and > 6.0 log Hepatitis A virus. |