| abstract |
The present invention provides a method of inhibitingnglucose metabolism deterioration in a mammal bynadministering a substituted aminopyrimidine having thenFormulan n whereinn R 1 , R 2 , and R 3 are, independently, hydrogen,nhalogen, C 1 -C 4 alkoxy, C 1 -C 4 alkylthio, C 1 -C 4 alkyl, or C 3 -C 5 -cycloalky; R 4 is hydrogen, formyl, acetyl, propionyl or butyryl; n provided that R 1 , R 2 and R 3 are not all hydrogen at thensame time; nor a pharmaceutically acceptable salt or solvate thereof. |