| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2828
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
1996-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f2a0d3ab248d349f946048d225079ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_695fed74aeb12ea4f63738e6f4bdfce6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e6f360985f8e6b002cf474679eff3f1 |
| publicationDate |
2004-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0852011-B1 |
| titleOfInvention |
ANTIBODIES SPECIFIC FOR NATIVE PrP?Sc |
| abstract |
An antibody is claimed which is characterised by its ability to bind the scrapie isoform of prion protein PrP-Sc in situ. Also claimed are: (1) an antibody which specifically binds to PrP-Sc produced by a process comprising: (a) synthesizing a library of antibodies on phage; (b) panning the library against a sample by bringing the phage into contact with a compsn. comprising prion proteins (PrP); (c) isolating phage which bind PrP-Sc protein; (2) a method of detecting human PrP-Sc in a source, comprising: (a) contacting a source suspected of contg. human PrP-Sc with an antibody which specifically binds 50% or more of human PrP-Sc in the source; and (b) determining whether the antibody binds specifically to any material in the source; and (3) an assay, comprising: (a) a support surface; and (b) an antibody bound to the surface of the support, the antibody characterised by an ability to bind native PrP-Sc in situ with a binding affinity of 107 l/mole or more. |
| priorityDate |
1995-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |