| abstract |
Compounds are disclosed having the formula (I), in which R<1>, R<2>, R<3> independently represent a hydrogen atom, a halogen atom, a hydroxy group, a hydroxyalkyl group, an alkyl group, an alkenyl group, an alkinyl group, an alkoxy group, an aralkyloxy group, an alkenyloxy group, an alkinyloxy group, a carboxyl group, an alkoxycarbonyl group, an alkenyloxycarbonyl group, an alkinyloxycarbonyl group, a carboxyalkyl group, an alkyloxycarbonylalkyl group, an alkenyloxycarbonylalkyl group or an allkinyloxycarbonylalkyl group; A stands for a straight- or branched-chain alkylene group that optionally bears substituents such as hydroxyl, carboxyl, alkoxycarbonyl groups or halogen atoms; X stands for a simple bond, an alkylene or alkylenoxy group; Y stands for a simple bond, a chalkogen atom or a carbonyl group; Z stands for a saturated or unsaturated, optionally substituted, heterocyclic or carbocyclic ring system, an optionally substituted amino group, an hydroxyl group, a carboxyl group, an alkoxycarbonyl group or an alkyl group; n equals 1 or 2; and m equals an integer from 0 to 4. Also disclosed are hydrates, solvates, physiologically tolerable salts of these compounds and their optical isomers, a process for preparing the same and medicaments that contain these compounds and are useful for treating thromboembolitic diseases. |