| abstract |
The present invention provides a process for preparing 3-norcephem compound represented by the formula (2), characterized in that a hydride reagent is acted on a halogenated beta -lactam compound represented by the formula (1) in the presence of a cuprous compound <CHEM> wherein R1 is a hydrogen atom, amino group or protected amino group, R2 is an aryl or substituted aryl, n is 0 to 2, R3 is a hydrogen atom or carboxylic acid protective group, X is a halogen atom, and Y is a halogen atom or a leaving group <CHEM> wherein R1 and R3 are as defined above.r |