abstract |
A monoclonal antibody which specifically reacts with D-monomernproduced by digesting human fibrinogen withngranulocyte elastase and D-domain containing digestionnproducts produced by digesting human stabilized fibrin withngranulocyte elastase, but does not react with fibrinogen, ornfragment X, Y or E produced by digesting fibrinogen withngranulocyte elastase is disclosed. The D-dimer or DD/Encomplex produced by digestion with granulocyte elastase in ansample from a living body can be analyzed without beingninterferred with fibrinogen, digestion products of fibrinogennwith plasmin, or digestion products of stabilized fibrin withnplasmin, using the monoclonal antibody. |