abstract |
The present invention discloses carbohydrates and carbohydrate analogs that bind to epidermal growth factor (EGF) receptors. Methods of using such carbohydrates or analogs for a variety of uses related to the EGF receptor are also provided. In preferred aspects of the present invention, methods for killing or inhibiting the growth of tumor cells with increased EGF receptor activity are disclosed. In another aspect of the invention, methods are provided for purifying an EGF receptor. In a further aspect of this invention, methods are provided for screening for a candidate molecule able to bind an EGF receptor. |