Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81edc3716e403e694de164ea154c0b95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73b46a19d9635f31a98d8919333159f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed0f934936c1de4f365849a4cdf5f6d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6c031f63af6086d7ba57f231e940f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26fd085c5a1985c9a7b9670153bbb7f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f0b75e848f79920963ff223f8e29d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd99c23fd242956c07c2833dc9a10dfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e945f929c817a42faf8fa02fef569f3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96619589c3502f443d01661310488f5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7159ff7dc72ffe3619e6728fe4fc29e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5152 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5154 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16 |
filingDate |
1996-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78cc6ce0b7ffa39e9e8bcd8701de1af2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a3416b0a934ca7eed2bf024a352b9a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13f0522546a653a159fcadb5cb6e73fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_721dfb3b7f8b76705794ab2edf7dbdbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61f5b19daa3d1f566313244726b06df4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea273f137d93c4bc4f37d590a9956b61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e36617190a4026008762e1909bd44e5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7188159eb4fb797a333279855fbd6287 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2483a90bd32658cb1291912c27a2f660 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b9347ab52cad166b5ad9372889326a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_925f04df3ebe2de71ac52108e6b2e4ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6206ce8c44bf04425ce77baea136722 |
publicationDate |
1998-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0839044-A1 |
titleOfInvention |
Dendritic-like cell/tumor cell hybrids and hybridomas for inducing an anti-tumor response |
abstract |
The invention provides dendritic-like cell/tumor cell hybridomas and pluralities of dendritic-like cell/tumor cell hybrids that confer tumor resistance in vivo. The hybrids and hybridomas are generated by the fusion of tumor cells with dendritic-like cells. For instance, immortal tumor cells from an autologous tumor cell line can be fused with autologous or HLA-matched allogeneic dendritic-like cells. Autologous tumor cell lines can be derived from primary tumors and from their metastases. Alternatively, immortal dendritic-like cells from an autologous or allogeneic HLA-matched dendritic-like cell line can be fused with autologous tumor cells. Autologous dendritic-like cell lines can be prepared from various sources such as peripheral blood and bone marrow. Dendritic-like cell/tumor cell hybridomas and pluralities of hybrids can be directly infused for active immunization of cancer patients against their residual tumor cells. The hybridomas and hybrids can also be used for the in vitro activation of autologous immune cells before their reinfusion into the patient for passive immunization against the tumor cells. |
priorityDate |
1995-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |