| abstract |
RsbW-1 polypeptides and DNA (RNA) encoding such RsbW-1 and a procedure fornproducing such polypeptides by recombinant techniques is disclosed. Also disclosed are methodsnfor utilizing such RsbW-1 for the treatment of infection, particularly bacterial infections.nAntagonists against such RsbW-1 and their use as a therapeutic to treat infections, particularlynbacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseasesnrelated to the presence of RsbW-1 nucleic acid sequences and the polypeptides in a host. Alsondisclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and forndetecting the polypeptide in a host. |