abstract |
Indanylidineacetylguanidines In nand their pharmaceutically acceptable salts nwherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and X have the meaningsngiven in the claims, are effective inhibitors of the cellular sodium/protonnantiport (Na + /H + exchanger), which, in numerous diseases (essentialnhypertension, atherosclerosis, diabetes and the like) is also increased innthose cells which are readily accessible for measurements, such as, fornexample, in erythrocytes, platelets or leukocytes. |