| abstract |
There is provided amino acid derivatives of formula (I), wherein p, q, R?1, R2, R3, R4¿, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants. |