| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdaa64756184e715af6cb25ebc318917 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-215 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-565 |
| filingDate |
1986-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e334e3c56f5f78b8ca63c8c7e136279d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e785805a995626b95e028430e98044ab |
| publicationDate |
1998-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0835661-A2 |
| titleOfInvention |
Human interferon-Beta2A for use as a medicament |
| abstract |
Human interferon-beta 2A and interferon-beta 2B are produced in purifiednform by recombinant DNA techniques. Two separate human genes havenbeen identified which code for the production of IFN-β 2A and IFN-β 2B ,nrespectively. The sequence of IFN-β 2A cDNA is established. Thesengenes and cDNA have been cloned into mammalian cells with an SV40nearly promoter sequence and such genomic clones are capable of producingnIFN-β 2A and IFN-β 2B . The antiviral activity of suchnrecombinant IFN-β 2A and IFN-β 2B is demonstrated as well as othernbiological activity identifying them as human interferons. It has beennshown that IFN-β 2 secretion is induced in human cells by growth-stimulatoryncytokines. n IFN-β 2A may be used as a medicament for influencing cell growth and differentiation.nIFN-β 2A may also be useful during terminal differentiation of cancer cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8071321-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1542609-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1542609-A2 |
| priorityDate |
1985-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |