| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc19d8d6ba9ad5c1fa5770341472b56 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
1990-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e36643c259afe294e108696aa560673f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d564844cc88eb4659d1af6ddc2b19df7 |
| publicationDate |
1998-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0832980-A1 |
| titleOfInvention |
Recombinant therapies for infection and hyperproliferative disorders |
| abstract |
The present invention provides polynucleotide constructs,ne.g. recombinant viral vectors, for treating a host cell forna hyperproliferative disorder or infection by an infectiousnagent, said infection or hyperproliferative disorder beingncharacterised by a human disease-associated trans-actingnregulatory factor capable of regulating expression of genes.nIn particular, the present invention provides such constructsncomprising:n (i) at least two tandem copies of a cis-actingnregulatory sequence which are controllable by said trans-actingnregulatory factor; and (ii) an effector gene under the control of said cis-actingnregulatory sequence the expression of which rendersnsaid cell susceptible to protection or destruction, saidneffector gene encoding a gene product which is capable ofnconverting a prodrug into its active drug form. |
| priorityDate |
1989-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |