abstract |
The present invention provides compounds ofnformula In nwhereinn R 1 is -H, -OH, -O(C 1 -C 4 alkyl), -OCO(C 1 -C 6 alkyl),n-OCOO(C 1 -C 6 alkyl), -OCOAr, -OCOOAr, or -OSO 2 (C 2 -C 6 alkyl); R 2 is -OH, -O(C 1 -C 4 alkyl), -OCO(C 1 -C 6 alkyl),-OCOO(C 1 -C 6 nalkyl), -OCOAr, -OCOOAr, or -OSO 2 (C 2 -C 6 alkyl); R 3 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl,ndimethyl-l-pyrrolidinyl, 4-morpholino,ndimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino;nand n is 2 or 3; nor a pharmaceutically acceptable salt or solvate thereof. |